Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study

Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study

Background: In kidney transplantation, evaluating HLA mismatches eplets-small patch of surface-exposed amino acids of the HLA molecule-antigen mismatch may not offer a better approach for assessing donor-recipient HLA mismatch and increasing the risk assessment and prediction of the results of transplantation.


Methods: To evaluate the effect of the number of mismatches Eplet (load mismatch) on the formation of de novo antibody donor specific HLA (DSA) and the results of transplantation, we conducted a cohort study which included recipients of renal grown successively transplanted in one center from March 2004 to February 2013 . We conducted a retrospective high resolution genotyping HLA loci of 926 pairs of transplantation and the use of computer algorithms to calculate HLAMatchmaker Eplet HLA mismatches.


Result: De novo DSAs occurred in 43 (4.6%) patients. Multivariable analysis showed a significant independent association between antibody-verified Eplet load mismatch and de novo DSA events and graft failure, mainly explained by DQ antibody Eplet effect is verified. Association with DQ antibody-verified discrepancy Eplet is linear, indefinitely safe where de novo DSA does not occur. Odds for T cell- or antibody-mediated rejection increased by 5% and 12%, respectively, per antibody-verified Eplet DQ mismatch.


Conclusion: Eplet mismatches in HLA-DQ confer substantial risk for de novo formation of DSA, graft rejection, and graft failure after kidney transplantation. Mismatches in other loci seem to have less effect. The results showed that HLA-DQ antibody Eplet mismatch load-verified personal can use to guide post-transplant immunosuppression. Adoption molecular match for DQA1 and DQB1 alleles can also help to minimize the de novo formation of DSA and potentially improve transplant outcome.

 Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study
Eplet Mismatch Load and De Novo Occurrence of Donor-Specific Anti-HLA Antibodies, Rejection, and Graft Failure after Kidney Transplantation: An Observational Cohort Study

Anti-Cancer Effect of 3-Hydroxy-β-Ionone Identified from Moringa oleifera Lam. Man leaves 15 squamous cell carcinoma cells

Squamous cell carcinoma is the most common type of cancer worldwide head and neck. Radiation and chemotherapy common treatment for patients; However, these drugs can have side effects and tumors develop drug resistance. effective treatments still require improvements for cancer patients. Here, we examined the effects of anti-cancer properties of Moringa oleifera (MO) Lam. leaf extract and its fractions, 3-hydroxy-β-ionone in SCC15 cells. SCC15 treated with and without MO leaf extract and its fractions.

MTT assay was used to determine cell viability in SCC15. cell cycle and apoptosis was evaluated by Muse ™ cell analyzer. colony formation and wound closure SCC15 analysis conducted in 6-well plates. Apoptotic markers were evaluated by immunoblotting. We found that an extract of moringa and 3-HBI significantly inhibit proliferation of SCC15. In addition, they induced apoptosis and cell cycle arrest in G2 / M phase in SCC15 compared with untreated controls. MO extract and 3-HBI also inhibit the colony formation and cell migration SCC15.

In addition, we observed upregulation of cleaved caspase-3 and Bax with downregulation of anti-apoptotic Bcl-2, which shows the induction of apoptosis of cancer cells. Our results show that extracts of MO and 3-HBI supplied anti-cancer properties by inhibiting the progression and induce apoptosis of SCC15.

Anti-Human Galectin-1 Antibody

102-P131 100 µg
EUR 245.7
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and anti-inflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

Anti-Human Galectin-1 Antibody

102-PA131AG 50 µg
EUR 157.5
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

Anti-Human Galectin-1 Antibody

102-PA131S 100 µg
EUR 126
Description: Galectin-1, also known as L14, BHL and galaptin, is a monomeric or homodimeric prototype galectin that is expressed in a variety of cells and tissues including muscle, heart, liver, prostate, lymph nodes, spleen, thymus, placenta, testis, retina, macrophages, B cells, T cells, dendritic cells, and tumor cells. It preferentially binds laminin, fibronectin, 90K/Mac2BP, CD45, CD43, CD7, CD2, CD3, and ganglioside GM1. Galectin-1 modulates cell growth and proliferation, either positively or negatively, depending on the cell type and activation status. It controls cell survival by inducing apoptosis of activated T cells and immature thymocytes. It modulates cytokine secretion by inducing Th2 type cytokines and inhibiting proinflammatory cytokine production. Galectin1 can also modulate cel-lcell as well as cell-lmatrix interactions and depending on the cell type and developmental stage, promote cell attachment or detachment. Galectin-1 has immunosuppressive and antiinflammatory properties and has been shown to suppress acute and chronic inflammation and autoimmunity. Human and mouse galectin1 share about 88% amino acid sequence similarity.

Human Galectin( Galectin) Elisa Kit

EK711568 96 Wells
EUR 0.18

Anti- Galectin-1 Antibody

GWB-6F6392 0.1 mg Ask for price

anti- Galectin-1 antibody

FNab03314 100µg
EUR 606.3
Description: Antibody raised against Galectin-1

anti- Galectin-1 antibody

FNab03315 100µg
EUR 658.5
Description: Antibody raised against Galectin-1

Human Galectin-1 (Gal-1) Antibody

30005-05111 150 ug
EUR 215

Human Galectin-1 (LGALS1)

1-CSB-EP012882HU
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  • 100ug
  • 10ug
  • 1MG
  • 200ug
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-1 (LGALS1)

1-CSB-EP012882HUb1
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  • 100ug
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  • 1MG
  • 200ug
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Description: Recombinant Human Galectin-1(LGALS1) expressed in E.coli

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-48T 48T Ask for price

Human Galectin-3(Galectin-3)ELISA Kit

YLA0216HU-96T 96T Ask for price

human anti-human galectin-3 mAb(2D)

E4A09H10-2D 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(5F)

E4A09H10-5F 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(A5)

E4A09H10-A5 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(G2)

E4A09H10-G2 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(H3)

E4A09H10-H3 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(T1)

E4A09H10-T1 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

human anti-human galectin-3 mAb(N13)

E4A09H10-N13 50ug
EUR 275
Description: Biotin-Conjugated, FITC-Conjugated , AF350 Conjugated , AF405M-Conjugated ,AF488-Conjugated, AF514-Conjugated ,AF532-Conjugated, AF555-Conjugated ,AF568-Conjugated , HRP-Conjugated, AF405S-Conjugated, AF405L-Conjugated , AF546-Conjugated, AF594-Conjugated , AF610-Conjugated, AF635-Conjugated , AF647-Conjugated , AF680-Conjugated , AF700-Conjugated , AF750-Conjugated , AF790-Conjugated , APC-Conjugated , PE-Conjugated , Cy3-Conjugated , Cy5-Conjugated , Cy5.5-Conjugated , Cy7-Conjugated Antibody

Anti Human Galectin-3 Polyclonal Antibody

KH040 each
EUR 778.8
Description: The Anti Human Galectin-3 Polyclonal Antibody is available in Europe and for worldwide shipping via Gentaur.

Recombinant Human Galectin-1

7-00427 10µg Ask for price

Recombinant Human Galectin-1

7-00428 50µg Ask for price

Recombinant Human Galectin-1

7-00429 1mg Ask for price

Recombinant Human Galectin-1

AP60482 100ug
EUR 449

Recombinant Human Galectin-1

HEOPP-0710 10ug Ask for price

RECOMBINANT HUMAN GALECTIN-1

GWB-BEA2B0 0.05 mg Ask for price

Recombinant Human Galectin-1

cyt-544-10g 10µg
EUR 60

Recombinant Human Galectin-1

cyt-544-1mg 1mg
EUR 1350

Recombinant Human Galectin-1

cyt-544-50g 50µg
EUR 145

Human Galectin 1 Protein

20-abx066725
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  • 100 ug
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  • 1 mg
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Human Galectin-1 Antibody Pair Set

ABPR-ZB244 5 plates, 15 plates Ask for price
Description: Quantitative determination of Human Galectin-1

Galectin-1, human recombinant

4648-10 each
EUR 170.4

Galectin-1, human recombinant

4648-1000 each
EUR 1977.6

Galectin-1, human recombinant

4648-50 each
EUR 314.4

Galectin-1 Human Recombinant

rAP-2252 Inquiry Ask for price

Human Galectin-1 ELISA Kit

EK5323 96 tests
EUR 599

Human Galectin-1 ELISA Kit

IHULGALS1KT each
EUR 702
Description: Human Galectin-1 ELISA Kit

Mouse Monoclonal anti-human Galectin-1

hAP-1228 50ug
EUR 400

Sheep Polyclonal anti-Human Galectin-1

hAP-5905 50ug
EUR 400

Anti-Mouse Galectin-1 Antibody

103-M223 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Human Galectin-1 (LEG1) Protein

abx690252-100g 100 µg
EUR 837.5

Human Galectin-1 (LEG1) Protein

abx690252-20g 20 µg
EUR 350

Human Galectin 1 (GAL1) ELISA

KT-15605 96 tests
EUR 952

Human Galectin-1 (LGALS1) Protein

abx670211-50ug 50 ug
EUR 661.2

Human Galectin 1 ELISA kit

E01A4669 96T
EUR 700
Description: ELISA

Human Galectin 1 ELISA kit

E01G0038-192T 192 tests
EUR 1524
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-48 1 plate of 48 wells
EUR 624
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA kit

E01G0038-96 1 plate of 96 wells
EUR 822
Description: A sandwich ELISA for quantitative measurement of Human Galectin 1 in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin 1 ELISA Kit

IHUGAL1KT each
EUR 667
Description: Human Galectin 1 ELISA Kit

Galectin-10, Human

E34M155H 5 μg
EUR 155

Galectin-12, Human

E34M156H 5 μg
EUR 155

Galectin-13, Human

E34M157H 5 μg
EUR 155

Galectin-14, Human

E34M158H 5 μg
EUR 155

Galectin-16, Human

E34M159H 5 μg
EUR 155

Galectin-2, Human

E34M149H 5 μg
EUR 155

Galectin-3, Human

E34M150H 5 μg
EUR 155

Galectin-4, Human

E34M151H 5 μg
EUR 155

Galectin-7, Human

E34M152H 5 μg
EUR 155

Galectin-8, Human

E34M153H 5 μg
EUR 155

Galectin-9, Human

E34M154H 5 μg
EUR 155

Galectin-3 Human

GWB-1FDCC0 0.05 mg Ask for price

Anti-Human Galectin-3 Antibody

101-M424 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Anti-Human Galectin-4 Antibody

101-M425 100 µg
EUR 399
Description: Galectin-4 is a member of the subfamily of galectins composed of two carbohydrate recognition domains having similar peptide chains. The galectins are a family of beta-galactoside-binding proteins having a role in modulating cell-cell and cell-matrix interactions, which inhibits chronic inflammations, GVHD, and allergic responses. LGALS4 expression is limited to small intestine, colon, and rectum, and it is underexpressed in colorectal cancer. LGALS4 binds as an endogenous ligand to glycosphingolipids having 3-O-sulfated Gal residues and bind as well to cholesterol-3-sulfate. LGALS4 takes part in cell adhesion. LGALS4 plays a role in crosslinking the lateral cell membranes of the surface-lining epithelial cells, thus supporting epithelial integrity against mechanical stress exerted by the bowel lume.

Anti-Human Galectin-8 Antibody

101-M427 100 µg
EUR 399
Description: LGALS8 is a prostate-specific antigen that is solely overexpressed in malignant tumors and thus is a supplementary specific identifier of malignancies. LGALS8 is part of the galectin gene family which facilitates both cell-cell and cell matrix interactions in a method parallel to the selectin subgroup of C-type lectins.

Anti-Human Galectin-3 Antibody

101-M747 100 µg
EUR 399
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

Anti-Human Galectin-7 Antibody

101-M748 100 µg
EUR 399
Description: Galectin-7 is a protein that in humans is encoded by the LGALS7 gene. The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell–cell and cell–matrix interactions. Differential and in situ hybridizations indicate that this lectin is specifically expressed in keratinocytes. It is expressed at all stages of epidermal differentiation (i.e., in basal and supra-basal layers). It is moderately repressed by retinoic acid. The protein was found mainly in stratified squamous epithelium. The antigen localized to basal keratinocytes, although it was also found, albeit at lower levels, in the supra-basal layers where it concentrated to areas of cell-to-cell contact. The cellular localization and it’s striking down-regulation in cultured keratinocytes imply a role in cell–cell and/or cell–matrix interactions necessary for normal growth control.

Anti-Human Galectin-3 Antibody

102-P228 100 µg
EUR 245.7
Description: The galectins constitute a large family of carbohydrate-binding proteins that function in many systems both intracellularly and following secretion. Galectins contain either one or two carbohydrate recognition domains (CRR) which mediate recognition of N-acetyl-lactosamine-containing glycoproteins. Some galectins exist in multiple isoforms due to alternative splicing. Individual galectins differ in their tissue distribution and in their carbohydrate-binding specificities.

anti-human Galectin-3 antibody

10-2887 250 ug
EUR 410
Description: Purified anti-human Galectin-3 antibody

Anti-human Galectin-3 antibody

STJ15100163 250 µg
EUR 403.2
Description: This monoclonal antibody is for studies of antigen expression in cells and tissue sections using immunocytochemistry and immunoprecipitation

Recombinant Human Galectin-1(LGALS1)

AP70493 1mg
EUR 1978

Recombinant Human Galectin-1 (LGALS1)

CSB-EP012882HU 1598 mg Ask for price

Recombinant Human Galectin-1 (LGALS1)

CSB-EP012882HUb1 1599 mg Ask for price

Recombinant Human Galectin-1 (LGALS1)

Z101845 15 µg
EUR 105
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Recombinant Human Galectin-1 (LGALS1)

Z101847 100 µg
EUR 270
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Recombinant Human Galectin-1 (LGALS1)

Z101849 1.0 mg
EUR 1135
Description: Galectin-1 is a member of the galectin family, and binds B-galactosidase moieties on glycoproteins or glycolipids. Galectins are primarily involved in modulation of cell-cell and cell-matrix interactions. Galectin-1 acts as a negative regulator of immunity, promoting immune suppression and lessening the inflammatory response. Galectin-1 binds CD45, CD3 and CD4, resulting in the inhibition of CD45 phosphatase dependant dephosphorylation of lyn kinase, as well as a number of other immune related receptors. Due to its function as a negative regulator of the immune response, and role inducing apoptosis in activated Th1 and Th17 cells, it is commonly found upregulated around malignant tumours. It has also been implicated as having a role in the development of immune tolerance during pregnancy, and is highly expressed at the maternal-fetal interface. As a dimer it down-regulates neutrophils by inducing exposure of phosphatidylserine, thereby marking the cell for apoptosis. It shares approximately 88% and 90% sequence similarity with mouse and rat galectin-1, respectively. Recombinant Human Galectin-1 is a 14.9kDa protein.

Human Galectin-1 ELISA ELISA Kit

E16HE0311 96T
EUR 1000

Human Galectin-1 Recombinant Protein

100-175 50 µg
EUR 196.35
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin-1 Recombinant Protein

100-175S 10 µg
EUR 92.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin-1 Recombinant Protein

400-015 50 µg
EUR 126
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Recombinant Human Galectin-1 Protein

E40KMP1041 20ug
EUR 495

Recombinant Human Galectin-1 Protein

PROTP09382-1 50ug
EUR 380.4
Description: Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with β-galactoside moieties. Galectin-1 is an animal lectin that has been shown to interact with CD3, CD4, and CD45. It induces apoptosis of activated T-cells and T-leukemia cell lines and inhibits the protein phosphatase activity of CD45. Recombinant human Galectin-1 is a 14.5 kDa protein containing 134 amino acid residues.

Human Galectin 10 Antibody

32652-05111 150 ug
EUR 215

Human Galectin 8 Antibody

33159-05111 150 ug
EUR 215

Human Galectin 2 Antibody

33165-05111 150 ug
EUR 215

Human Galectin 13 Antibody

33175-05111 150 ug
EUR 215

Human Galectin 1 (LGALS1) Protein

abx066725-100g 100 µg
EUR 512.5

Human Galectin 1 (LGALS1) Protein

abx066725-10g 10 µg
EUR 212.5

Human Galectin 1 (LGALS1) Protein

abx066725-50g 50 µg
EUR 362.5

Human Galectin 1 (LGALS1) Protein

abx670211-100g 100 µg
EUR 450

Human Galectin-1(LGALS1) ELISA kit

E01A4871 96T
EUR 700
Description: ELISA

Human Galectin-1(LGALS1) ELISA kit

E01G0448-192T 192 tests
EUR 1524
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-48 1 plate of 48 wells
EUR 624
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

E01G0448-96 1 plate of 96 wells
EUR 822
Description: A competitive ELISA for quantitative measurement of Human Galectin-1(LGALS1) in samples from blood, plasma, serum, cell culture supernatant and other biological fluids. This is a high quality ELISA kit developped for optimal performance with samples from the particular species.

Human Galectin-1(LGALS1) ELISA kit

EKC33776-48T 48T
EUR 535.99

Human Galectin-1(LGALS1) ELISA kit

EKC33776-5x96T 5x96T
EUR 3637.08

Human Galectin-1(LGALS1) ELISA kit

EKC33776-96T 96T
EUR 765.7

Human Galectin-1(LGALS1) Elisa Kit

EK712878 96 Wells
EUR 0.3

Human Galectin-1 (LGALS1) ELISA Kit

AE35699HU-48Tests 48 Tests
EUR 325
Description: Human (Homo sapiens)

Human Galectin-1 (LGALS1) ELISA Kit

AE35699HU-96Tests 96 Tests
EUR 610
Description: Human (Homo sapiens)

Human Galectin-1(LGALS1) ELISA kit

CSB-EL012882HU-24T 1 plate of 24 wells
EUR 198
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1 (LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.

Human Galectin-1(LGALS1) ELISA kit

1-CSB-EL012882HU
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  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
Description: Quantitativesandwich ELISA kit for measuring Human Galectin-1(LGALS1) in samples from serum, plasma, tissue homogenates, cell lysates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.

Human Galectin 1 (GAL1) CLIA Kit

20-abx190336
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  • 10 × 96 tests
  • 5 × 96 tests
  • 96 tests

Human Galectin 1 (GAL1) CLIA Kit

abx196676-96tests 96 tests
EUR 990

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-48T 48T
EUR 414.89

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-5x96T 5x96T
EUR 2815.33

Human Galectin 1 (GAL1) CLIA Kit

EKN51025-96T 96T
EUR 592.7

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-48T 48T
EUR 666.82

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-5x96T 5x96T
EUR 4524.85

Human Galectin 1 (GAL1) CLIA Kit

EKU09914-96T 96T
EUR 952.6

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 6777.36
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 663.31
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 896.16
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1)CLIA Kit

SCA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 3672.72
Description: This is Double-antibody Sandwich Chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1) in serum, plasma and other biological fluids.

Human Galectin 1 (GAL1) CLIA Kit

4-SCA321Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Double-antibody Sandwich chemiluminescent immunoassay for detection of Human Galectin 1 (GAL1)Serum, plasma and other biological fluids

Human Galectin-1 (Gal-1) Antibody (Biotin Conjugate)

30005-05121 150 ug
EUR 315

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-24Tests 24 Tests
EUR 180
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-48Tests 48 Tests
EUR 546
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests 96 Tests
EUR 682
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests10 96 Tests *10
EUR 6820
Description: Sandwich

Human GAL1 -Galectin 1 - CLIA Kit

E-CL-H0704-96Tests5 96 Tests *5
EUR 3410
Description: Sandwich

Galectin-1

AP89417 1mg
EUR 2640

Galectin-1

AP84615 1mg
EUR 2640

Galectin-1

AP84729 1mg
EUR 2640

Galectin-1

AP84945 1mg
EUR 2640

Galectin-1

AP85083 1mg
EUR 2640

Human Galectin 1 (GAL1) ELISA kit

201-12-3227 96 tests
EUR 528
Description: A quantitative ELISA kit for measuring Human in samples from biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu 96T
EUR 422
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-48T 48T
EUR 574.8
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

DLR-GAL1-Hu-96T 96T
EUR 745.2
Description: A sandwich quantitative ELISA assay kit for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

EKL57418-5x96T 5x96T
EUR 3452.78

Human Galectin 1 (GAL1) ELISA Kit

EKL57418-96T 96T
EUR 726.9

Human Galectin 1 (GAL1) ELISA Kit

EKU11884-48T 48T
EUR 474.74

Human Galectin 1 (GAL1) ELISA Kit

EKU11884-5x96T 5x96T
EUR 3221.45

Human Galectin 1 (GAL1) ELISA Kit

EKU11884-96T 96T
EUR 678.2

Human Galectin 1 (GAL1) ELISA Kit

EKU04314-48T 48T
EUR 395.36

Human Galectin 1 (GAL1) ELISA Kit

EKU04314-5x96T 5x96T
EUR 2682.8

Human Galectin 1 (GAL1) ELISA Kit

EKU04314-96T 96T
EUR 564.8

Human Galectin 1 (GAL1) ELISA Kit

EKN52995-48T 48T
EUR 295.33

Human Galectin 1 (GAL1) ELISA Kit

EKN52995-5x96T 5x96T
EUR 2004.03

Human Galectin 1 (GAL1) ELISA Kit

EKN52995-96T 96T
EUR 421.9

Human Galectin 1 (GAL1) ELISA Kit

EKN45425-48T 48T
EUR 269.71

Human Galectin 1 (GAL1) ELISA Kit

EKN45425-5x96T 5x96T
EUR 1830.18

Human Galectin 1 (GAL1) ELISA Kit

EKN45425-96T 96T
EUR 385.3

Human Galectin 1 (GAL1) ELISA Kit

DL-GAL1-Hu 96T
EUR 402
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

EK14143 96Т
EUR 768

Human Galectin 1 ELISA Kit (GAL1)

RK01436 96 Tests
EUR 625.2

Human Galectin 1(GAL1)ELISA Kit

QY-E04196 96T
EUR 433.2

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-48T 48T
EUR 432.39
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-48Tests 48 Tests
EUR 600

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-96T 96T
EUR 617.72
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RDR-GAL1-Hu-96Tests 96 Tests
EUR 830.4

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-48T 48T
EUR 411.8
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-48Tests 48 Tests
EUR 573.6

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-96T 96T
EUR 588.3
Description: serum, plasma, tissue homogenates, cell lysates, cell culture supernatants and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

RD-GAL1-Hu-96Tests 96 Tests
EUR 794.4

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-10x96wellstestplate 10x96-wells test plate
EUR 4091.29
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-1x48wellstestplate 1x48-wells test plate
EUR 442.1
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-1x96wellstestplate 1x96-wells test plate
EUR 580.15
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

SEA321Hu-5x96wellstestplate 5x96-wells test plate
EUR 2250.68
Description: This is Double-antibody Sandwich Enzyme-linked immunosorbent assay for detection of Human Galectin 1 (GAL1) in serum, plasma, tissue homogenates and other biological fluids.

Human Galectin 1 (GAL1) ELISA Kit

4-SEA321Hu
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  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
Description: Enzyme-linked immunosorbent assay based on the Double-antibody Sandwich method for detection of Human Galectin 1 (GAL1) in samples from serum, plasma, tissue homogenates and other biological fluids with no significant corss-reactivity with analogues from other species.

Human Galectin 1 (GAL1) ELISA kit

YLA3564HU-48T 48T Ask for price

Human Galectin 1 (GAL1) ELISA kit

YLA3564HU-96T 96T Ask for price

Human Galectin 1 (GAL1) ELISA Kit

SL2544Hu 96 Tests
EUR 468

anti- Galectin-3 antibody

FNab03316 100µg
EUR 606.3
Description: Antibody raised against Galectin-3

anti- Galectin-3 antibody

FNab03317 100µg
EUR 658.5
Description: Antibody raised against Galectin-3

anti- Galectin-7 antibody

FNab03318 100µg
EUR 606.3
Description: Antibody raised against Galectin-7

Human GAL1 (Galectin 1) ELISA Kit

EKE60660-5x96T 5x96T
EUR 3124.08

Human GAL1 (Galectin 1) ELISA Kit

EKE60660-96T 96T
EUR 657.7

Human GAL1(Galectin 1) ELISA Kit

ELK1312-48T 48T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GAL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GAL1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human GAL1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human GAL1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human GAL1(Galectin 1) ELISA Kit

ELK1312-96T 96T Ask for price
Description: The test principle applied in this kit is Sandwich enzyme immunoassay. The microtiter plate provided in this kit has been pre-coated with an antibody specific to Human GAL1. Standards or samples are added to the appropriate microtiter plate wells then with a biotin-conjugated antibody specific to Human GAL1. Next, Avidin conjugated to Horseradish Peroxidase (HRP) is added to each microplate well and incubated. After TMB substrate solution is added, only those wells that contain Human GAL1, biotin-conjugated antibody and enzyme-conjugated Avidin will exhibit a change in color. The enzyme-substrate reaction is terminated by the addition of sulphuric acid solution and the color change is measured spectrophotometrically at a wavelength of 450nm ± 10nm. The concentration of Human GAL1 in the samples is then determined by comparing the OD of the samples to the standard curve.

Human GAL1(Galectin 1) ELISA Kit

RE1588H-48wells 48 wells
EUR 116.55

Human GAL1(Galectin 1) ELISA Kit

RE1588H-96wells 96 wells
EUR 161.55

Human Galectin-1 PicoKine ELISA Kit

EK0762 96 wells
EUR 510
Description: For quantitative detection of human Galectin-1 in cell culture supernates, cell lysates, serum and plasma (heparin, EDTA).

Galectin 1 (GAL1) Polyclonal Antibody (Human)

4-PAA321Hu01
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  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
Description: A Rabbit polyclonal antibody against Human Galectin 1 (GAL1)

Galectin-1 Antibody

3596-100 each
EUR 379.2

Galectin-1 Antibody

3596-30T each
EUR 175.2

Galectin-1 antibody

CAF50544-100ug 100ug
EUR 312

Galectin-1 Antibody

GWB-3E9423 0.1 mg Ask for price

Galectin-1, Antibody

GWB-4616D2 1 ml Ask for price

Galectin-1 Antibody

R34524-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lectin, galactose binding, soluble 1; Lgals1

Galectin-1 Antibody

R34565-100UG 100 ug
EUR 339.15
Description: Additional name(s) for this target protein: Lgals1

Human LGALS1/ Galectin-1 ELISA Kit

E1450Hu 1 Kit
EUR 515
Description: 14 kDa laminin-binding protein,S-Lac lectin 1,14 kDa lectin,Beta-galactoside-binding lectin L-14-I,Galaptin,HBL,HPL,Lactose-binding lectin 1,Lectin galactoside-binding soluble 1,Putative MAPK-activating protein PM12,HLBP14

Human LGALS1(Galectin-1) ELISA Kit

EH0626 96T
EUR 628.92
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.469 ng/ml

Human LGALS1(Galectin-1) ELISA Kit

EKF59005-48T 48T
EUR 396.9

Human LGALS1(Galectin-1) ELISA Kit

EKF59005-5x96T 5x96T
EUR 2693.25

Human LGALS1(Galectin-1) ELISA Kit

EKF59005-96T 96T
EUR 567

Human LGALS1 / Galectin-1 ELISA Kit

E2165h 96T
EUR 536

Human Galectin-1 Flow Cytometry Assay -

HX87445 96 Tests
EUR 310

Rat Monoclonal anti-mouse Galectin-1

mAP-0081 100ug
EUR 250

Human Galectin 1 (LGALS1) CLIA Kit

abx196676-100l 100 µl Ask for price


Hesperidin hydrolyzate (HHS) is produced by the hydrolysis of hesperidin (HDN) in the previous study. Potential component in HHS identified by LC-MS, and the minor component (MCS) in HHS isolated. Antioxidant activity with the capacity of the radical-scavenging capacity reduces test and β-carotene-linoleic, anti-inflammatory effects by inhibiting the production of NO from RAW 264.7 cells, and α-glucosidase inhibitory effects of HDN, HHS, MCS and henperetin (HTN) was investigated in the research this

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