Anti-inflammatory drugs degradation during LED-UV 365 photolysis of free chlorine: roles of reactive oxidative species and formation of disinfection by-products

Anti-inflammatory drugs degradation during LED-UV 365 photolysis of free chlorine: roles of reactive oxidative species and formation of disinfection by-products

ight-emitting diode (LED) which are environmentally friendly with longer life compared to traditional mercury lamp. This study investigated the anti-inflammatory drugs non-steroidal (NSAIDs) – phenacetin (PNT) and acetaminophen (ACT) – the deletion for LED-UV (365 nm) photolysis of free available chlorine (FAC). PNT degradation and ACT for LED-UV365 / FAC treatment at pH 5.5 to 8.5 followed pseudo-first-order kinetics. The presence of hydroxyl radicals (OH ·), reactive chlorine species (RCS), and ozone (O3, change of O (3P)) filtered by using a scavenger ethanol (EtOH), tert-butanol (TBA), and 3- Buten-2ol, and 4-hydroxy-2,2,6,6-tetramethylpiperidine (TEMP), and is measured by the kinetics of competition with probing compound nitrobenzene (NB), benzoic acid (BA), 1,4-dimethoxybenzene (Dmob). Higher pH will cause a decrease ·

OH contribution and increased contribution to the PNT and ACT FAC degradation. It has been determined that the contribution of PNT and ACT O3 degradation of less than 5% for all pH, and O3 (P) react to EtOH with second-order constant of 1.52 × 109 M-1s-1. LED-UV365 / FAC system reduces the formation of five typical CX3-R type of disinfection by-products (DBPs) as well as cytotoxicity and genotoxicity of water samples at pH 5.5 and 8.5, compared with FAC alone.

A decrease in the formation of DBPs resulting from the rapid decomposition of the irradiation LED FAC-UV365. A decent reaction path forming DBPs in LED-systems UV365 / FAC checked by density functional theory (DFT). To decay FAC for LED-UV365 / FAC effluents from waste water, in 15 minutes the rest of the FAC was 0.8 mg / L (lower than the limit of 0.2 mg / L) after the initial FAC was 2.0 mg / L. the results showed that more testing on the balance of the pollutant removal efficiency targets, FAC residual and fees should be explored in a system of LED-UV365 / FAC for the application.

 Anti-inflammatory drugs degradation during LED-UV 365 photolysis of free chlorine: roles of reactive oxidative species and formation of disinfection by-products
Anti-inflammatory drugs degradation during LED-UV 365 photolysis of free chlorine: roles of reactive oxidative species and formation of disinfection by-products

Anti-Cancer Effect of 3-Hydroxy-β-Ionone Identified from Moringa oleifera Lam. Man leaves 15 squamous cell carcinoma cells

Squamous cell carcinoma is the most common type of cancer worldwide head and neck. Radiation and chemotherapy common treatment for patients; However, these drugs can have side effects and tumors develop drug resistance. effective treatments still require improvements for cancer patients. Here, we examined the effects of anti-cancer properties of Moringa oleifera (MO) Lam.

leaf extract and its fractions, 3-hydroxy-β-ionone in SCC15 cells. SCC15 treated with and without MO leaf extract and its fractions. MTT assay was used to determine cell viability in SCC15. cell cycle and apoptosis was evaluated by Muse ™ cell analyzer. colony formation and wound closure SCC15 analysis conducted in 6-well plates.

Anti-IL-6 Antibody

A00102-1 100ug
EUR 432
Description: Rabbit Polyclonal IL-6 Antibody. Validated in Neu, IHC, WB and tested in Human.

Anti-IL-31 Antibody

A08339-1 100ug/vial
EUR 334

Anti-IL-17B Antibody

A10846-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-17B Antibody (IL17B) detection.tested for IHC in Human, Rat.

Anti-MonoMethylH3R2me1-(R2) antibody

STJ24010 100 µl
EUR 393
Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3.

Anti-GABAB R2 antibody

STJ96379 200 µl
EUR 197
Description: Rabbit polyclonal to GABAB R2.

Anti-TNF-R2 antibody

STJ96053 200 µl
EUR 197
Description: Rabbit polyclonal to TNF-R2.

Anti-PKA R2 (6A9)

YF-MA10721 100 ug
EUR 363
Description: Mouse monoclonal to PKA R2

Anti-PKA R2 (3C7)

YF-MA14876 100 ug
EUR 363
Description: Mouse monoclonal to PKA R2

Anti-IL-6 Monoclonal Antibody

M00102-1 100ug
EUR 455
Description: Mouse Monoclonal IL-6 Antibody. Validated in Flow Cytometry, WB and tested in Human.

Anti-IL-17A Monoclonal Antibody

M00421-1 100ug
EUR 455
Description: Mouse Monoclonal IL-17A Antibody. Validated in WB and tested in Human.

Anti-IL-2/IL2 Antibody

A00387-1 100ug/vial
EUR 294

Anti-IL-8 Monoclonal Antibody

A00423-1 100ul
EUR 397
Description: Mouse Monoclonal Antibody for IL-8 Antibody (CXCL8) detection. Tested with IHC in Human, Mouse, Rat.

Anti-IL-22/IL22 Antibody

A00963-1 100ug/vial
EUR 294

Anti-IL-3R beta Antibody

A02219-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for IL-3R beta Antibody (CSF2RB) detection.tested for WB in Human, Mouse, Rat.

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-1mg 1 mg
EUR 897

Rat Anti-Mouse IL-12 p75 Monoclonal antibody, clone R2-9A5

CABT-L4486-5mg 5 mg
EUR 2405

Anti-Human IL-17F Biotin Conjugated Monoclonal Antibody

B02062-1 100ug
EUR 432
Description: Mouse Monoclonal Human IL-17F Biotin Conjugated Antibody. Validated in IHC, WB and tested in Human.

IL-1 β

E13-003-1 10μg
EUR 213

IL-1 α

E13-029-1 10μg
EUR 213

Anti-IL-32A Antibody Peroxidase Conjugated

A03286-1 100ug
EUR 455
Description: Rabbit Polyclonal IL-32A Antibody Peroxidase Conjugated. Validated in WB and tested in Human.

Anti-GABA(B) R2 Purified

11-551-C100 0.1 mg
EUR 204

IL-1 beta, rat recombinant

P1019-1 1 mg
EUR 7288
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells. Both IL-1? and IL-1? bind to the same receptor and have similar biological properties.

Human Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EI2200-1 96 Well Plate
EUR 477

Human Interleukin-1-alpha (IL-1-alpha) AssayMax ELISA Kit

EI2301-1 96 Well Plate
EUR 477

IL-1beta, human recombinant

P1018-1 1 mg
EUR 5061
Description: Interleukin 1 beta (IL-1?) is a proinflammatory cytokine and is produced by activated macrophages, monocytes, keratinocytes and other epithelial cells

IL-2, human recombinant

P1020-1 1 mg
EUR 1156
Description: Interleukin 2 (IL2) is a secreted cytokine that is important for the proliferation of T and B lymphocytes and is produced by activated CD4+ and CD8+ T cells, gamma ? T cells, B cells, dendritic cells and eosinophils. IL-2 plays a critical role in immune responses against pathogenic infection

IL-3, human recombinant

P1021-1 1 mg
EUR 4017
Description: Interleukin 3 (IL-3) is a pleiotropic cytokine produced by activated T cells, mast cells and eosinophils, and stimulates the proliferation and differentiation of pluripotent hematopoietic stem cells, and committed progenitor cells of the megakaryocyte

IL-7, human recombinant

P1024-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Notoginsenoside R2

HY-N0909 10mg
EUR 463

Stipuleanoside R2

TBZ1475 unit Ask for price

Notoginsenoside R2

TN028181 20mg Ask for price

Anti-Phospho-GABAB R2 (Ser783) Antibody

P03830 100ul
EUR 398
Description: Rabbit Polyclonal Phospho-GABAB R2 (Ser783) Antibody. Validated in IF, WB and tested in Mouse, Rat.

Recombinant Rat IL-1 Beta Protein

PROTQ63264-1 10ug
EUR 317
Description: IL-1β is a proinflammatory cytokine produced in a variety of cells including monocytes, tissue macrophages, keratinocytes and other epithelial cells. Both IL-1α and IL-1β binds to the same receptor and has similar if not identical biological properties. These cytokines have a broad range of activities including, stimulation of thymocyte proliferation, by inducing IL-2 release, B-cell maturation and proliferation, mitogenic FGF-like activity and the ability to stimulate the release of prostaglandin and collagenase from synovial cells. However, whereas IL-1β is a secreted cytokine, IL-1α is predominantly a cell-associated cytokine. Recombinant rat IL-1β is a 17.4 kDa protein containing 153 amino acid residues.

Canine IL-1 beta Recombinant Protein

R00101-1 5ug/vial
EUR 259
Description: IL-1 beta (IL-1β) is a member of the interleukin 1 family of cytokines. The IL-1 beta cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. Canine IL-1 beta Recombinant Protein is purified interleukin-1 beta cytokine produced in yeast.

Canine IL-1 alpha Recombinant Protein

R01144-1 5ug/vial
EUR 259
Description: IL-1 alpha (IL-1α, IL-1F1) is a member of the interleukin 1 family of cytokines. IL-1 alpha is an inflammatory cytokine active in the initiation of the inflammatory reaction and in driving Th1 and Th17 inflammatory responses. Canine IL-1 alpha Recombinant Protein is purified interleukin-1 alpha cytokine produced in yeast.

Polyclonal Goat anti-GST μ-form

GST-ANTI-2 50 uL
EUR 280

Polyclonal Goat anti-GST p-form

GST-ANTI-3 50 uL
EUR 280

IL-1-beta Interleukin-1 betaHuman Recombinant Protein

PROTP01584-1 Regular: 10ug
EUR 317
Description: Interleukin-1 beta Human Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 153 amino acids and having a molecular mass of 17000 Dalton.;The IL-1b is purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Human Recombinant Protein, His Tag

PROTP01583-1 Regular: 20ug
EUR 317
Description: IL-1A Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 159 amino acids fragment (113-271) with an amino-terminal hexahistidine tag and having a total molecular mass of 22.5kDa. ;The Interleukin-1 alpha His-tag is purified by proprietary chromatographic techniques.

Recombinant Human IL-24 Protein

PROTQ13007-1 20ug
EUR 317
Description: IL-24 is a secreted glycoprotein belonging to the IL-10 structural family of cytokines. It is produced by a variety of cell types, including B cells, CD4+ cells, NK cells, lymph node DCs, monocytes, and melanoma cells. IL-24 can signal through the IL20R1/IL20R2 and IL22R1/IL20R2 receptors to initiate a signaling cascade which includes the induction of JAK1/STAT3 phosphorylation. IL-24 is, functionally, a pleiotropic protein but is generally characterized as an anti-cancer cytokine that can selectively inhibit growth of a wide variety of human cancer cells through activities that include the induction of differentiation and apoptosis, and the suppression of angiogenesis and cell proliferation. Recombinant human IL-24 is an 18.9 kDa glycoprotein, containing 161 amino acid residues, including a C-terminal His-tag.

Recombinant Human IL-31 Protein

PROTQ6EBC2-1 10ug
EUR 317
Description: Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant IL-31 is a 15.8 kDa protein containing 141 amino acid residues.

Recombinant Human IL-17D Protein

PROTQ8TAD2-1 25ug
EUR 317
Description: IL-17D is a disulfide-linked homodimer of two 185 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17D has the ability to stimulate the production of IL-6, IL-8, and GM-CSF and inhibits hemopoiesis of myeloid progenitor cells in colony forming assays. Recombinant human IL-17D is a 40.5 kDa disulfide-linked homodimer of two 185 amino acid polypeptide chains.

Recombinant Human IL-22 Protein

PROTQ9GZX6-1 10ug
EUR 317
Description: IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10R-β/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family. Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked homodimeric protein containing of two 146 amino acid polypeptide chains.

Recombinant Human IL-17E Protein

PROTQ9H293-1 25ug
EUR 317
Description: IL-17E is a disulfide-linked homodimer of two 145 amino acid polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region, but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17E stimulated secretion of IL-8, and induces activation of the transcription factor NF-κB in cells that express the IL-17BR receptor. Recombinant human IL-17E is a 33.8 kDa disulfide-linked homodimer of two 145 amino acid polypeptide chains.

Recombinant Human IL-20 Protein

PROTQ9NYY1-1 10ug
EUR 317
Description: IL-20 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. IL-20 is a hematopoietic growth factor capable of stimulating colony formation by CD34+ multipotential progenitors, but not by other progenitor cells. IL-20 signals through a receptor system composed of type I IL-20R-α and type II IL-20R-β. Over-expression of IL-20 in keratinocytes expressing both receptor subunits has been implicated in the induction of inflammatory skin disease. Recombinant human IL-20 is a 35.2 kDa homodimeric protein consisting of two 153 amino acid polypeptide chains.

Recombinant Human IL-19 Protein

PROTQ9UHD0-1 10ug
EUR 317
Description: IL-19 belongs to the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences but they are dissimilar in their biological functions. Preliminary data suggests that IL-19 is a proinflammatory cytokine because it up-regulates IL-6 and TNF-α and induces apoptosis through TNF-α. IL-19 signals through the type I IL-20R. Human and murine IL-19 share 71% amino acid sequence identity. Recombinant human IL-19 is a 17.9 kDa protein containing 153 amino acid residues. In solution IL-19 exists predominantly as a non-disulfide-linked dimer.

Recombinant Human IL-12 Protein

PROTP29459-1 10ug
EUR 317
Description: IL-12 is a potent regulator of cell mediated immune responses and it induces IFN-γ production by NK and T cells. It is produced by activated monocytes/macrophage cells, B lymphocytes and connective tissue type mast cells. Among its biological activities IL-12 promotes the growth and activity of activated NK, CD4+ and CD8+ cells and induces the development of IFN-γ producing Th1 cells. Recombinant Human IL-12 is a 75.0 kDa heterodimeric glycoprotein consisting of disulfide-linked 35 kDa (p35) and 40 kDa (p40) subunits (503 total amino acid residues).

IL-10, human recombinant protein

P1028-1 1 mg
EUR 6731
Description: Interleukin-10 (IL-10) is an immunosuppressive cytokine produced by macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the synthesis of proinflammatory cytokines such as IL-1 and TNF-? and proliferation of T cells

IL-15, human recombinant protein

P1029-1 1 mg
EUR 5339
Description: Interleukin 15 (IL-15) is an immunomodulating cytokine mainly produced by adherent peripheral blood mononuclear cells, fibroblasts and epithelial cells and stimulates the proliferation of T lymphocytes.

IL-17A, human recombinant protein

P1030-1 1 mg
EUR 4156
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO).

IL-18, human recombinant protein

P1032-.1 100 µg
EUR 780
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-18, human recombinant protein

P1032-1 1 mg
EUR 5061
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine produced by monocyte/macrophages, osteoblasts and keratinocytes, as a proprotein which is proteolytically processed to its active form by caspase-1. Human IL-18 can enhance NK cell activity in PBMC cultures.

IL-21, human recombinant protein

P1033-1 1 mg
EUR 6522
Description: Interleukin-21 (IL-21) is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. IL-21 induces the differentiation of T-cell-stimulated B-cells into plasma cells and memory B-cells, apoptotic effects in naïve B-cells.

Recombinant Murine IL-17 (IL-17A) Protein

PROTQ62386-1 25ug
EUR 317
Description: The originally described IL-17 protein, now known as IL-17A, is a disulfide linked homodimer, secreted by activated T-cells that act on stromal cells to induce production of proinflammatory and hematopoietic bioactive molecules. Today, IL-17 represents a family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles. The six known members of this family, IL-17A through IL-17F, are secreted as homodimers. IL-17A exhibits cross-species bioactivity between human and murine cells. Recombinant murine IL-17A is a 30.0 kDa disulfide-linked homodimer of two 133 amino acid polypeptide chains.

Anti-GABAB Receptor (Ser783), R2-Subunit antibody

STJ120094 100 µl
EUR 526

ApoE R2, CF

PR15062CF 50 ug
EUR 461

R-Notoginsenoside R2

N2244-20 20 mg
EUR 572
Description: Extracted from Panax Notoginseng dried roots;Store the product in sealed, cool and dry condition

TNF- R2 Antibody

ABF0364 100 ug
EUR 438

TNF- R2 Antibody

ABF0365 100 ug
EUR 438

TNF-R2 Antibody

AF0364 200ul
EUR 304
Description: TNF-R2 antibody detects endogenous levels of total TNF-R2.

TNF-R2 Antibody

AF0365 200ul
EUR 304
Description: TNF-R2 antibody detects endogenous levels of total TNF-R2.

PKA R2 Antibody

AF6724 100ul
EUR 350

IL-8 (77 a.a.), human recombinant

P1026-1 1 mg
EUR 4226
Description: Interleukin-8 (IL-8) is a proinflammatory CXC chemokine produced by macrophages, epithelial cells. IL-8 is also synthesized by endothelial cells, which store IL-8 in their storage vesicles, the Weibel-Palade bodies

Mouse Interleukin-1 beta (IL-1 beta) AssayMax ELISA Kit

EMI2200-1 96 Well Plate
EUR 477

Anti-IL-1 RII antibody

STJ16100664 100 µg
EUR 742

Anti-IL-1 beta Antibody

A00101-2 1mg
EUR 1232
Description: Rabbit Polyclonal IL-1 beta Antibody. Validated in IP, IHC, WB and tested in Human.

Anti-IL-1 Alpha Antibody

A01144 1mg
EUR 1232
Description: Rabbit Polyclonal IL-1 Alpha Antibody. Validated in WB and tested in Human.

Anti-IL-1 beta antibody

STJ73078 100 µg
EUR 359

anti- IL 1 alpha antibody

FNab04208 100µg
EUR 548.75
Description: Antibody raised against IL 1 alpha

Anti-IL 1 alpha antibody

PAab04208 100 ug
EUR 386

IL-8 Interleukin-8 (1-77 a.a) Human Recombinant Protein (CXCL8)

PROTP10145-1 Regular: 25ug
EUR 317
Description: Interleukin-8 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8904 Dalton. ;The IL-8 is purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Human Recombinant Protein, His Tag

PROTP18510-1 Regular: 50ug
EUR 682
Description: IL1Ra Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 152 amino acids fragment (26-177) and having a total molecular mass of 21.63kDa with an amino-terminal hexahistidine tag. ;The IL-1Ra His is purified by proprietary chromatographic techniques.

IL-2

E13-013-1 10μg
EUR 161

IL-4

E13-015-1 10μg
EUR 161

IL-6

E13-016-1 10μg
EUR 161

IL-1-alpha Interleukin-1 alpha Mouse Recombinant Protein, His Tag

PROTP01582-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.4kDa.;IL 1 alpha is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

IL-1-beta Interleukin-1 beta Mouse Recombinant Protein, His Tag

PROTP10749-1 Regular: 25ug
EUR 317
Description: Interleukin-1 beta Mouse Recombinant produced in E.Coli is a non-glycosylated, Polypeptide chain containing 189 amino acids and having a molecular mass of 21 kDa. ;The IL-1b is fused to His-Tag and purified by proprietary chromatographic techniques.

IL-1-alpha Interleukin-1 alpha Rat Recombinant Protein, His Tag

PROTP16598-1 Regular: 20ug
EUR 317
Description: IL 1 alpha Rat Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids (115-270 a.a) and having a molecular mass of 20.2kDa.

Anti-IL-1F6 / IL-36

PAab04239 100 ug
EUR 412

IL-17 Interleukin-17 Human Recombinant Protein

PROTQ16552-1 Regular: 25ug
EUR 317
Description: Interleukin-17A Human Recombinant produced in E.Coli is a homodimeric, non-glycosylated polypeptide chain containing a total of 264 amino acids (2 chains of 132 aa) and having a molecular mass of 31kDa.  ;The IL-17 is purified by proprietary chromatographic techniques.

IL-29 Interleukin-29 Human Recombinant Protein

PROTQ8IU54-1 Regular: 20ug
EUR 317
Description: IL-29 human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 181 amino acids and having a molecular mass of 20 kDa.

IL-28A Interleukin-28A Human Recombinant Protein

PROTQ8IZJ0-1 Regular: 20ug
EUR 317
Description: IL-28A human recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 175 amino acids and having a molecular mass of 19.6 kDa.

IL-17B Interleukin 17B Human Recombinant Protein

PROTQ9UHF5-1 Regular: 25ug
EUR 317
Description: Interleukin-17B Human Recombinant produced in E.Coli is a homodimeric, non-disulfide-linked polypeptide chain containing a total of 322 amino acids (2 chains of 161aa) and having a molecular mass of 36.5kDa. The IL-17B is purified by proprietary chromatographic techniques.

IL-4 Interleukin-4 Human Recombinant Protein

PROTP05112-1 Regular: 20ug
EUR 317
Description: Interleukin-4 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 130 amino acids and having a molecular mass of 15kDa. ;The IL-4 is purified by proprietary chromatographic techniques.

IL-6 Interleukin-6 Human Recombinant Protein

PROTP05231-1 Regular: 20ug
EUR 317
Description: Interleukin-6 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 184 amino acids and having a molecular mass of 21000 Dalton. ;The IL6 is purified by proprietary chromatographic techniques.

IL-3 Interleukin-3 Human Recombinant Protein

PROTP08700-1 Regular: 10ug
EUR 317
Description: Interleukin-3 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 133 amino acids and having a molecular mass of 15000 Dalton. The IL-3 is purified by proprietary chromatographic techniques.

IL-9 Interleukin-9 Human Recombinant Protein

PROTP15248-1 Regular: 10ug
EUR 317
Description: Interleukin-9 Human Recombinant produced in E.Coli is a single, non-glycosylated single polypeptide chain containing 127 amino acids and having a molecular mass of 14,004 Dalton. ;The IL-9 is purified by proprietary chromatographic techniques.

IL-11 Interleukin-11 Human Recombinant Protein

PROTP20809-1 Regular: 10ug
EUR 317
Description: Interleukin-11 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 179 amino acids and having a molecular mass of 19256.29 Dalton. ;The IL-11 is purified by proprietary chromatographic techniques.

IL-1RA Interleukin-1 Receptor Antagonist Mouse Recombinant Protein

PROTP25085-1 Regular: 20ug
EUR 317
Description: IL1 ra Mouse Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 153 amino acids and having a molecular mass of 17.4kDa. ;The IL1ra is purified by proprietary chromatographic techniques.

IL-4, murine recombinant

P1022-1 1 mg
EUR 4504
Description: IL-4 is a pleiotropic cytokine produced by activated T lymphocytes, basophils, mast cells and bone marrow stromal cells. IL-4 plays an important role in the regulation of isotype switching, differentiation of precursor T helper cells and induction of IgE production in B lymphocytes.

IL-6, rat recombinant

P1023-1 1 mg
EUR 6940
Description: Interleukin-6 (IL-6) is a pleiotropic cytokine produced by activated T cells, monocytes, fibroblasts, endothelial cells, keratinocytes and macrophages, and plays an critical role in host defense by regulating immune and inflammatory responses.

IL-7, murine recombinant

P1025-1 1 mg
EUR 6940
Description: Interleukin-7 (IL-7) is a potent lymphoid cell growth factor produced by bone marrow and thymic stromal cells, spleen cells and keratinocytes. IL7 stimulates the proliferation of Pre-B, Pro-B and early T cells.

Anti-Phospho-PKA R2 (S99) Rabbit Monoclonal Antibody

P03911 100ug/vial
EUR 397
Description: Rabbit Monoclonal Phospho-PKA R2 (S99) Antibody. Validated in IP, IF, WB and tested in Human, Mouse, Rat.

Anti-citrulline-Histone H3-R2/R8/R17 antibody

STJ11100254 100 µl
EUR 393

Rabbit Anti-Rat GABAb-R2 (GBR2) Antiserum #2

GBR22-S 100 ul
EUR 457

Anti-Apaf-1 (human) Monoclonal Antibody (2E12)

M00889-1 100ug
EUR 432
Description: Rat Monoclonal Apaf-1 (human) Antibody (2E12). Validated in ELISA, IP, IF, WB and tested in Human.

IL-10 Interleukin-10 Human Recombinant Protein, His

PROTP22301-1 Regular: 10ug
EUR 317
Description: Interleukin-10 Human Recombinant produced in E.Coli is single, a non-glycosylated, Polypeptide chain containing 181 amino acids fragment (19-178) and having a total molecular mass of 20.94kDa with a 20 amino acids N-Terminal His tag. ;The IL-10 His-Tag protein is purified by proprietary chromatographic techniques.

Human Interleukin-6 (IL-6) AssayMax ELISA Kit

EI1006-1 96 Well Plate
EUR 477

Human Interleukin-8 (IL-8) AssayMax ELISA Kit

EI1008-1 96 Well Plate
EUR 477

Human Interleukin-10 (IL-10) AssayMax ELISA Kit

EI3010-1 96 Well Plate
EUR 477

Human Interleukin-15 (IL-15) AssayMax ELISA Kit

EI3015-1 96 Well Plate
EUR 477

Human Interleukin-33 (IL-33) AssayMax ELISA Kit

EI3033-1 96 Well Plate
EUR 477

Anti-IL-1 beta/IL1B Antibody

A00101 100ug/vial
EUR 294

GABAB R2 Polyclonal Antibody

ES8063-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against GABAB R2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

GABAB R2 Polyclonal Antibody

ES8063-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against GABAB R2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, WB, ELISA

20(R)-Notoginsenoside R2

HY-N2049 1mg
EUR 179

IFN-?R2 Polyclonal Antibody

ES4097-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against IFN-?R2 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

IFN-?R2 Polyclonal Antibody

ES4097-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against IFN-?R2 from Human. This antibody is tested and validated for WB, ELISA, IHC, WB, ELISA

TNF-R2 Polyclonal Antibody

ES3622-100ul 100ul
EUR 279
Description: A Rabbit Polyclonal antibody against TNF-R2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

TNF-R2 Polyclonal Antibody

ES3622-50ul 50ul
EUR 207
Description: A Rabbit Polyclonal antibody against TNF-R2 from Human/Mouse/Rat. This antibody is tested and validated for WB, ELISA, IHC, IF, WB, ELISA

FGF-R2-Allophycocyanin Labeled

FC15015 100 Tests
EUR 448

VEGF R2 (FLK1/KDR)

RA25011 500 ul
EUR 611

GABAB R2 Polyclonal Antibody

ABP57064-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of GABAB R2 from Human, Mouse, Rat. This GABAB R2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human GABAB R2 around the non-phosphorylation site of S893

GABAB R2 Polyclonal Antibody

ABP57064-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of GABAB R2 from Human, Mouse, Rat. This GABAB R2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human GABAB R2 around the non-phosphorylation site of S893

GABAB R2 Polyclonal Antibody

ABP57064-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of GABAB R2 from Human, Mouse, Rat. This GABAB R2 antibody is for WB, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from human GABAB R2 around the non-phosphorylation site of S893

TNF-R2 Polyclonal Antibody

ABP52623-003ml 0.03ml
EUR 158
Description: A polyclonal antibody for detection of TNF-R2 from Human, Mouse, Rat. This TNF-R2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TNF-R2 at AA range: 350-430

TNF-R2 Polyclonal Antibody

ABP52623-01ml 0.1ml
EUR 289
Description: A polyclonal antibody for detection of TNF-R2 from Human, Mouse, Rat. This TNF-R2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TNF-R2 at AA range: 350-430

TNF-R2 Polyclonal Antibody

ABP52623-02ml 0.2ml
EUR 414
Description: A polyclonal antibody for detection of TNF-R2 from Human, Mouse, Rat. This TNF-R2 antibody is for WB, IHC-P, IF, ELISA. It is affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogenand is unconjugated. The antibody is produced in rabbit by using as an immunogen synthesized peptide derived from the C-terminal region of human TNF-R2 at AA range: 350-430

Gingipain R2 (RGPB) Antibody

20-abx319597
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

PKA-R2 beta Antibody

20-abx012820
  • EUR 314.00
  • EUR 98.00
  • EUR 398.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 200 ug
  • 300 µg

PKA R2 Rabbit mAb

A3889-100ul 100 ul
EUR 410

PKA R2 Rabbit mAb

A3889-200ul 200 ul
EUR 571

PKA R2 Rabbit mAb

A3889-20ul 20 ul
EUR 221

PKA R2 Rabbit mAb

A3889-50ul 50 ul
EUR 287

GABA(B) R2 Antibody

48296-100ul 100ul
EUR 333

GABA(B) R2 Antibody

48296-50ul 50ul
EUR 239

TNF-R2 Blocking Peptide

AF0364-BP 1mg
EUR 195

TNF-R2 Blocking Peptide

AF0365-BP 1mg
EUR 195

IFN Gamma R2 antibody

70R-6702 50 ug
EUR 467
Description: Rabbit polyclonal IFN Gamma R2 antibody

IL1 R2 Recombinant Protein

96-437 0.1 mg
EUR 516.5
Description: Interleukin-1 receptor type 2 (IL1R2) is also known as CD121 antigen-like family member B (CDw121b), IL-1 type II receptor, Interleukin-1 receptor type II, belongs to the interleukin-1 receptor family. Two distinct types of IL1 receptors which are able to bind IL1 specifically have been identified, designated as IL1RI (IL1RA) and IL1RII (IL1RB). IL1R2 is non-signaling receptor for IL1A, IL1B and IL1RN, reduces IL1B activities. Serves as a decoy receptor by competetive binding to IL1B and preventing its binding to IL1R1. IL1R2 modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN. The secreted IL1R2 recruits secreted IL1RAP with high affinity; this complex formation may be the dominant mechanism for neutralization of IL1B by secreted/soluble receptors.

Transferrin R2 Recombinant Protein

97-029 0.05 mg
EUR 595.25
Description: Transferrin receptor protein 2 (TFR2) is a single-pass type II membrane protein with a protease associated (PA) domain, an M28 peptidase domain and a transferrin receptor-like dimerization domain. The mutations in TFR2 gene have been associated with hereditary hemochromatosis type III. Furthermore, TFR2 is involved in the uptake of transferrin-bound iron into cells by endocytosis, although its role is minor compared to transferrin receptor 1.

VEGF R2 Recombinant Protein

97-070 0.1 mg
EUR 542.75
Description: Kinase insert domain receptor (KDR) is also known as CD309, FLK1, VEGFR, VEGFR2, and is one of the subtypes of VEGFR. VEGF receptors are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. The VEGF receptors have an extracellular portion consisting of 7 immunoglobulin-like domains, a single transmembrane spanning region and an intracellular portion containing a split tyrosine-kinase domain. VEGF-A binds to VEGFR-1 (Flt-1) and VEGFR-2 (KDR/Flk-1). VEGFR-2 appears to mediate almost all of the known cellular responses to VEGF.The function of VEGFR-1 is less well defined, although it is thought to modulate VEGFR-2 signaling. Another function of VEGFR-1 may be to act as a dummy/decoy receptor, sequestering VEGF from VEGFR-2 binding (this appears to be particularly important during vasculogenesis in the embryo). In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions.

20(R)-Notoginsenoside R2

TRS0085 20mg Ask for price

TRAIL-R2 Recombinant Protein

90-259 50 ug
EUR 474.5
Description: TRAIL-R2 (DR5; CD262) is a receptor for the cytotoxic ligand TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappaB.

TRAIL R2 Recombinant Protein

91-302 0.05 mg
EUR 338
Description: TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. The adapter molecule FADD recruits caspase-8 to the activated receptor and is required for the apoptosis mediated by TNFRSF10B. TNFRSF10B is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. This single-pass transmembrane protein contains two cysteine-rich repeat units in its extracellular region, followed by a transmembrane segment and a cytoplasmic tail containing a typical “death domain”. TNFRSF10B expression is regulated by the tumor suppressor p53. It is also indicated that the activation of NF-kappa-B can be promoted by TNFRSF10B.

TRAIL R2 Recombinant Protein

91-904 0.05 mg
EUR 364.25
Description: TNFRSF10B is a member of the TNF-receptor superfamily, and contains an intracellular death domain. This receptor can be activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL/APO-2L), and transduces apoptosis signal. The adapter molecule FADD recruits caspase-8 to the activated receptor and is required for the apoptosis mediated by TNFRSF10B. TNFRSF10B is expressed in a number of cell types, and to particularly high levels in lymphocytes and spleen. This single-pass transmembrane protein contains two cysteine-rich repeat units in its extracellular region, followed by a transmembrane segment and a cytoplasmic tail containing a typical “death domain”. TNFRSF10B expression is regulated by the tumor suppressor p53. It is also indicated that the activation of NF-kappa-B can be promoted by TNFRSF10B.

TRAIL R2 Recombinant Protein

92-400 0.05 mg
EUR 490.25
Description: Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to TRAIL-R1 (DR-4). TNFRSF10B is highly expressed in heart, lung, lymphocytes, spleen and kidney. In addition, it is regulated by the tumor suppressor p53. TNFRSF10B is the receptor for the cytotoxic ligand TNFSF10/TRAIL. It promotes the activation of NF-kappa-B and is essential for ER stress-induced apoptosis. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases mediating apoptosis.

VEGF R2 Recombinant Protein

92-490 0.05 mg
EUR 490.25
Description: Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the regulation of angiogenesis, vascular development, vascular permeability, and embryonic hematopoiesis. It also plays an essential role in promoting proliferation, survival, migration and differentiation of endothelial cells, reorganization of the actin cytoskeleton. VEGFR2 is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo.The adaptor protein SHB has been shown to interact with VEGFR2 in receptor tyrosine kinase signaling. In addition, VEGFR2 is able to interact with HIV-1 extracellular Tat protein upon VEGF activation, and seems to enhance angiogenesis in Kaposi's sarcoma lesions. VEGF R2 is thought to be the primary inducer of VEGF-mediated blood vessel growth, while VEGF R3 plays a significant role in VEGF-C and VEGF-D-mediated lymphangiogenesis.

PKA-R2 beta Antibody

AF6952 100ul
EUR 350

His-IL-3

E13-014-1 10μg
EUR 161

His-IL-10

E13-019-1 10μg
EUR 161

His-IL-22

E13-028-1 10μg
EUR 213

IL-2-Fc

E13-m007-1 10μg
EUR 310

Anti-IL-36

PAab04274 100 ug
EUR 412

Recombinant Human VEGF R2/KDR Protein

RP00084 20 μg
EUR 202

IFN -gamma R2 ELISA KIT|Human

EF010951 96 Tests
EUR 689

Recombinant Murine IL-11 Protein

PROTP47873-1 10ug
EUR 317
Description: IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts. It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system. IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells. It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury. Recombinant Murine IL-11 is a 19.1 kDa protein consisting of 179 amino acid residues.

Recombinant Rat IL-7 Protein

PROTP56478-1 10ug
EUR 317
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant rat IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Recombinant Rat IL-15 Protein

PROTP97604-1 10ug
EUR 317
Description: IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2. IL-15 exerts its biological activites primarily on T cells. It is also essential in the development, survival and activation of NK cells. Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I. Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells. Recombinant rat IL-15 is a 13.5 kDa protein consisting of 115 amino acid residues.

Recombinant Rat IL-5 Protein

PROTQ08125-1 10ug
EUR 317
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Murine IL-31 Protein

PROTQ6EAL8-1 10ug
EUR 317
Description: IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It signals through a receptor complex comprised of GPL (GP130-like, IL-31RA) and OSMR (Oncostatin M receptor). GPL/OSMR signaling is a strong activator of STAT3 and STAT5, and can also activate STAT1, Jak1, and Jak2 signaling pathways. IL-31 regulated immune responses have been implicated in skin physiology and inflammatory skin diseases. Recombinant murine IL-31 is a 15.8 kDa protein containing 140 amino acid residues.

Recombinant Murine IL-17F Protein

PROTQ7TNI7-1 25ug
EUR 317
Description: IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F also regulates cartilage matrix turnover and inhibits angiogenesis. Recombinant murine IL-17F is a disulfide-linked homodimer of 30 kDa, consisting of two 134 amino acid residue chains.

Recombinant Murine IL-21 Protein

PROTQ9ES17-1 10ug
EUR 317
Description: IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include induction of differentiation of T-cells-stimulated-B-cells into plasma cells and memory B-cells, stimulation (in conjunction) with IL-4 of IgG production, and induction of apoptotic effects in naïve B-cells and stimulated B-cells in the absence of T-cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the γ chain (γc) found in other cytokine receptors including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.

Recombinant Murine IL-5 Protein

PROTP04401-1 25ug
EUR 317
Description: IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant murine IL-5 is a 26.2 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.

Recombinant Murine IL-4 Protein

PROTP07750-1 20ug
EUR 317
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant murine IL-4 is a 13.5 kDa globular protein containing 121 amino acid residues.

Recombinant Murine IL-7 Protein

PROTP10168-1 10ug
EUR 317
Description: IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.

Recombinant Murine IL-9 Protein

PROTP15247-1 10ug
EUR 317
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant murine IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

Recombinant Murine IL-10 Protein

PROTP18893-1 10ug
EUR 317
Description: IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant murine IL-10 is an 18.7 kDa protein of 161 amino acid residues.

Recombinant Rat IL-4 Protein

PROTP20096-1 20ug
EUR 317
Description: IL-4 is a pleiotropic cytokine that regulates diverse T and B cell responses including cell proliferation, survival and gene expression. Produced by mast cells, T cells and bone marrow stromal cells, IL-4 regulates the differentiation of naive CD4+ T cells into helper Th2 cells, characterized by their cytokine-secretion profile that includes secretion of IL-4, IL-5, IL-6, IL-10, and IL-13, which favor a humoral immune response. Another dominant function of IL-4 is the regulation of immunoglobulin class switching to the IgG1 and IgE isotypes. Excessive IL-4 production by Th2 cells has been associated with elevated IgE production and allergy. Recombinant rat IL-4 is a 14.0 kDa globular protein containing 126 amino acid residues.

Recombinant Murine IL-13 Protein

PROTP20109-1 10ug
EUR 317
Description: IL-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells, and also by mast cells and NK cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human and murine IL-13 is cross-species reactive. Recombinant murine IL-13 is a 12.3 kDa protein consisting of 111 amino acid residues.

Recombinant Rat IL-6 Protein

PROTP20607-1 10ug
EUR 317
Description: IL-6 is a pleiotropic cytokine that plays an important role in host defense by regulating immune and inflammatory responses. Produced by T cells, monocytes, fibroblasts, endothelial cells and keratinocytes, IL-6 has diverse biological functions. It stimulates B-cell differentiation and antibody production, synergizes with IL-3 in megakaryocyte development and platelet production, induces expression of hepatic acute-phase proteins, and regulates bone metabolism. IL-6 signals through the IL-6 receptor system that consists of two chains, IL-6R α and gp130. Murine IL-6 is inactive on human cells, while both human and murine are equally active on murine cells. Recombinant rat IL-6 is a 21.7 kDa protein containing 187 amino acid residues.

Recombinant Rat IL-10 Protein

PROTP29456-1 10ug
EUR 317
Description: IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNFα. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 active on murine cells, but murine IL-10 is inactive on human cells. Recombinant rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.

Chicken IL-10 Recombinant Protein

R00021-1 5ug/vial
EUR 259
Description: IL-10 is an anti-inflammatory cytokine and a member of the IL-10 family of cytokines, which have indispensable functions in many infectious and inflammatory diseases. Chicken IL-10 Recombinant Protein is purified interleukin-10 produced in yeast.

Canine IL-13 Recombinant Protein

R00077-1 5ug/vial
EUR 259
Description: IL-13 is an important mediator of allergic inflammation and disease. In addition to effects on immune cells, IL-13 is implicated as a central mediator of the physiologic changes induced by allergic inflammation in many tissues. Canine IL-13 Recombinant Protein is purified interleukin-13 produced in yeast.

Canine IL-6 Recombinant Protein

R00102-1 5ug/vial
EUR 259
Description: Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. Canine IL-6 Recombinant Protein is purified interleukin-6 produced in yeast.

Chicken IL-18 Recombinant Protein

R00124-1 5ug/vial
EUR 259
Description: Interleukin-18 (IL-18) is a proinflammatory cytokine that belongs to the IL-1 superfamily. IL-18 works together with IL-12 to induce cell-mediated immunity following infection, and IL-18 is also able to induce severe inflammatory reactions, which suggests its role in certain inflammatory disorders. Chicken IL-18 Recombinant Protein is purified interleukin-18 produced in yeast.

Equine IL-15 Recombinant Protein

R00212-1 5ug/vial
EUR 259
Description: Interleukin-15 (IL-15) is a cytokine with structural similarity to IL-2 that is secreted by mononuclear phagocytes following infection by virus(es). This cytokine induces cell proliferation of natural killer cells. Equine IL-15 Recombinant Protein is purified interleukin-15 produced in yeast.

Chicken IL-4 Recombinant Protein

R00230-1 5ug/vial
EUR 259
Description: IL-4 has many biological roles, including the stimulation of activated B-cell and T-cell proliferation, and the differentiation of CD4+ T-cells into Th2 cells. It is a key regulator in humoral and adaptive immunity. Chicken IL-4 Recombinant Protein is purified interleukin-4 produced in yeast.

Canine IL-2 Recombinant Protein

R00387-1 5ug/vial
EUR 259
Description: Interleukin-2 (IL-2) is a cytokine produced by T-helper cells in response to antigenic or mitogenic stimulation. It is required for T-cell proliferation and other activities crucial to the regulation of the immune response. Canine IL-2 Recombinant Protein is purified interleukin-2 produced in yeast.

Canine IL-17A Recombinant Protein

R00421-1 5ug/vial
EUR 259
Description: IL-17A is a member of the IL-17 family of cytokines, whose members are involved in numerous immune regulatory functions. IL-17 induces the production of many other cytokines, chemokines, and prostaglandins. Canine IL-17A Recombinant Protein is purified interleukin-17A produced in yeast.

Canine IL-8 Recombinant Protein

R00423-1 5ug/vial
EUR 259
Description: Interleukin-8 (IL-8), also known as CXCL8, is an ELR-positive CXC family member chemokine produced by macrophages and other cell types such as epithelial cells. ELR-positive CXC chemokines such as IL-8 specifically induce the migration of neutrophils, and interact with chemokine receptors CXCR1 and CXCR2. Canine IL-8 Recombinant Protein is purified interleukin-8 produced in yeast.

Canine IL-21 Recombinant Protein

R00459-1 5ug/vial
EUR 259
Description: The cytokine interleukin-21 (IL-21) regulates the proliferation and differentiation of T and B lymphocytes, modulates the cytotoxic activity and survival of NK and CD8+ T cells, and suppresses the maturation of dendritic cells. Canine IL-21 Recombinant Protein is purified interleukin-21 produced in yeast.

Canine IL-1ra Recombinant Protein

R00651-1 5ug/vial
EUR 259
Description: Interleukin-1 Receptor Antagonist Protein (IL-1F3, IL-1ra) belongs to the IL-1 family of cytokines, whose members play key roles in the development and regulation of inflammation. IL-1 receptor antagonist (IL-1ra; IL-1F3) reduces inflammation by blocking the binding of the agonist receptor ligands. Canine IL-1 Receptor Antagonist Recombinant Protein is purified interleukin-1 receptor antagonist protein (IL-1F3, IL-1ra) produced in yeast.

Rabbit IL-22 Recombinant Protein

R00963-1 5ug/vial
EUR 259
Description: IL-22 is produced by activated DC and T cells and initiates innate immune responses against bacterial pathogens, especially in epithelial cells such as respiratory and gut epithelial cells. IL-22 likely plays a role in the coordinated response of both adaptive and innate immune systems.

Canine IL-5 Recombinant Protein

R01086-1 5ug/vial
EUR 259
Description: The IL-5 cytokine has a key role in regulating eosinophil development and is responsible for selective terminal differentiation of eosinophils. It is associated with the cause of several allergic diseases including allergic rhinitis and asthma. Canine IL-5 Recombinant Protein is purified interleukin-5 produced in yeast.

Chicken IL-16 Recombinant Protein

R01635-1 5ug/vial
EUR 259
Description: Interleukin 16 (IL-16) is a pleiotropic cytokine that has been characterized as a chemoattractant for certain immune cells expressing the cell surface molecule CD4, and it has effects on mixed lymphocyte reaction and inhibition of HIV viral replication. Chicken IL-16 Recombinant Protein is purified interleukin-16 produced in yeast.

Chicken IL-17F Recombinant Protein

R02062-1 5ug/vial
EUR 259
Description: IL-17F induces the production of many other cytokines, chemokines, and prostaglandins from many cell types (fibroblasts, endothelial cells, epithelial cells, keratinocytes and macrophages). IL-17F has been shown to have a pro-inflammatory role in asthma. Chicken IL-17F Recombinant Protein is purified interleukin-17F produced in yeast.

Recombinant Rat IL-9 Protein

PROTD4A8I9-1 10ug
EUR 317
Description: IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin’s disease. Recombinant rat IL-9 is a 14.3 kDa protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.

IL-17A, rat recombinant protein

P1031-1 1 mg
EUR 4156
Description: Interleukin-17A (IL-17A) is a proinflammatory cytokine produced by Th17 cells. IL-17 regulates the activities of NF-kappaB and mitogen-activated protein kinases and stimulates the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as the production of nitric oxide (NO)

Anti-PARP-1 Antibody

A00122-1 100ul
EUR 397
Description: Rabbit Polyclonal PARP-1 Antibody. Validated in ELISA, IP, IF, WB and tested in Human, Mouse.

Anti-Presenilin 1 Antibody

A00138-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Presenilin 1 Antibody (PSEN1) detection. Tested with WB, IHC in Human, Mouse, Rat.

Anti-PAI-1 Antibody

A00637-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for PAI-1 Antibody (SERPINE1) detection.tested for WB in Human, Mouse, Rat.

Anti-Flk-1 Antibody

A00901-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Flk-1 Antibody (KDR) detection.tested for WB in Human, Mouse.

Anti-EDG-1 Antibody

A01502-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for EDG-1 Antibody (S1PR1) detection.tested for WB in Human, Mouse, Rat.

Anti-ROBO-1 Antibody

A01530-1 100ug
EUR 455
Description: Rabbit Polyclonal ROBO-1 Antibody. Validated in IF, IHC, WB and tested in Human, Mouse, Rat.

Anti-TFIIIB90-1 Antibody

A03761-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for TFIIIB90-1 Antibody (BRF1) detection.tested for WB in Human, Mouse.

Anti-Atrophin-1 Antibody

A03828-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Atrophin-1 Antibody (ATN1) detection. Tested with WB in Human, Mouse, Rat.

Anti-CNG-1 Antibody

A05494-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for CNG-1 Antibody (CNGA1) detection. Tested with WB in Human, Mouse, Rat.

Anti-Periphilin 1 Antibody

A06996-1 100ul
EUR 397
Description: Rabbit Polyclonal Antibody for Periphilin 1 Antibody (PPHLN1) detection.tested for WB in Human, Mouse.

Anti-Lyl-1 Antibody

A07491-1 100ul
EUR 397
Description: Rabbit Polyclonal Lyl-1 Antibody. Validated in IHC and tested in Human, Mouse, Rat.

Apoptotic markers were evaluated by immunoblotting. We found that an extract of moringa and 3-HBI significantly inhibit proliferation of SCC15. In addition, they induced apoptosis and cell cycle arrest in G2 / M phase in SCC15 compared with untreated controls. MO extract and 3-HBI also inhibit the colony formation and cell migration SCC15. In addition, we observed upregulation of cleaved caspase-3 and Bax with downregulation of anti-apoptotic Bcl-2, which shows the induction of apoptosis of cancer cells. Our results show that extracts of MO and 3-HBI supplied anti-cancer properties by inhibiting the progression and induce apoptosis of SCC15.

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